logo.jpg (2912 bytes)

health_banner.jpg


     

July-Aug & Sept-Oct 2002
download.gif (450 bytes)

news_home.jpg
editorial1.gif
lead_story.jpg
briefs.jpg
book_review.jpg
campaign.jpg
letters.jpg
news_arcive.jpg
writetous.jpg
health_home.jpg
cse_home.jpg

 

briefs1.gif (1467 bytes)

PRODUCT WATCH

devil.jpg (4979 bytes)
Return of the devil

Dangerous drugs like thalidomide that were banned for their toxicity have been re-incarnated to treat cancer and other diseases. Labelled as a "miracle drug", thalidomide was known to be an effective tranquilliser without any side effects. The drug was first synthesised by Ciba in 1953 to treat anxiety and morning sickness in pregnant women. Marketed as Distaval, the drug was banned in 1962 after scientists confirmed that it led to birth defects such as retardation and deformed limbs. More than 12,000 children in 46 countries had been affected by then, with only 8,000 of them surviving
past the first year of life. The actual mechanism of how the drug worked remains a mystery .

Despite its ban in 1962, thalidomide has been on restricted sales globally. It been prescribed for relief from painful lesions in leprosy, mouth and genital ulcers and cancer. Dabur India has acquired the rights to manufacture and market thalidomide to treat cancer and leprosy lesions. S Ganguly, senior clinical research scientist at Dabur India, Sahibabad office, mentions that extreme precaution is being taken to see that the drug is marketed to the right patient. It would be available only at cancer institutions and accessible for leprologists from suffering leprosy patients. The marketing is to be restricted to a few dealers who would be authorised to sell the drug and who will maintain detailed records to track the prescribing doctors and the patient alike. A 24-hour toll free help line will also be set up for patients

The marketing of thalidomide is going to be under close scrutiny by consumer watchdogs. One slip and the horror would well be repeated.

chipped.jpgHeavily chipped
A study led by Eric Williams and his team at the United Nations University in Tokyo has found that a 2 gramme microchip is equivalent to 1.6 kilogrammes of fossil fuel, 72 grammes of chemicals and 32 kilogrammes of water. Looking into all the chemicals including coal, which are involved in turning raw quartz into a 32 MB RAM microchip, the team found the chip manufacturing required more fuels and solvents because of its tiny size and the need to keep it free from dirt and dust. Making a typical car required only about twice its weight in fossil fuels. According to Eric Williams, "In order to produce one memory chip that weighs two grams, the total amount of materials and fossil fuels required to make that chip is 1,400 grams. That’s 700 times the weight of the original chip." The environmental costs of manufacturing a chip thus far outweigh that of even making a car. With new advances in technology and changing of computers every two years, the environmental impact of owning a computer increases drastically.The focus now has to shift from making chips that run on less power to manufacturing those that require less energy than it does at the present.

Mercurial tempers
Each mercury fever thermometer when broken or thrown away is a threat to health. The one-gram of mercury found in one thermometer is enough to pollute a 20-acre lake, says Michael Bender, Director of the Mercury Policy Project, USA.

Mercury is used in lamps, batteries and electrical equipment, as well as in thermometers and dental fillings. Concern over its presence in the atmosphere arises since mercury is known to cause permanent damage to the brain, nervous system and kidneys. Almost indestructible, mercury when put along with other waste into landfill sites, can easily seep through the groundwater and from there into rivers, lakes and the sea. It can also evaporate into the air, especially if the waste is incinerated.

Though mercury is produced naturally in rocks, soil and volcanoes, industrialisation has boosted up the production of this heavy metal almost three times. Almost 50 to 70 per cent of the 5,000 to 10,000 tonnes of mercury found in the atmosphere is due to human activities. In its evaporated form, mercury can travel for thousands of miles. Since it is know to accumulate in cold places high contamination levels of mercury are to be found in Arctic regions, and especially among fish and animals there. In water, mercury transforms naturally into methyl mercury, a highly toxic compound that gets absorbed by humans and animals. Because it then accumulates up the food chain sea fishes can accumulate large quantities of mercury in their tissue. Pregnant mothers and their fetuses are particularly sensitive to the effects of mercury. According to the Centres for Disease Control (CDC), Atlanta, USA, one-in-ten women of childbearing age have mercury levels in their bodies above what is considered protective for a developing fetus.

children.jpg Threatened children
A study conducted by Joseph Laquatra, associate professor of design and environmental analysis in the New York State College of Human Ecology at Cornell, in the US, has found children belonging to lower socio-economic status more prone to threats from indoor air pollutants. Their houses have higher levels of radon, lead and mould than those occupied by higher income households. If these children then spend the rest of the day exposed to the same pollutants in a childcare facility, they are at a significantly higher risk for falling sick due to lead poisoning, cancer, asthma attacks and allergies. Studying 328 houses and 75 childcare facilities in six nonmetropolitan counties of New York State, homes of lower income residents were also found to contain higher levels of carbon monoxide. Lack of an effective ventilation fan further aggravates the pollutant level. These houses also had asbestos problems and presence of basement mould. Mould is a known trigger for allergies and asthma. Exposure to lead, asbestos, radon and carbon monoxide can lead to early death.

Cancer clusters
Factors like where a woman lives at birth and puberty may have an impact on her risk of developing breast cancer later. A study conducted by Jo Freudenheim, professor in the department of social and preventive medicine in the University of Buffalo’s school of medicine and biomedical sciences, USA, finds that women who developed breast cancer were more likely to have lived closer together at birth and at their first menstruation than women who did not develop breast cancer. This suggests a possible linkage between breast cancer and early environmental exposure to potential carcinogens.

Identifying these places and exposures is one way of proving these linkages. In that respect, geographers and epidemiologists are working on a computerised mapping programme wherein details about residential data along with the distance between the surrounding environment comprising of steel mills, chemical factories, petrol pumps and toxic waste sites that have been in the existence between the two counties between 1918-1980 will be weighed against with the birth and menarche details of the women. This information will then be compared for women with or without cancer. Early data collected and calculated reveals the greatest clustering of cancer cases at the time of menarche. This could be because breast tissue may be more sensitive to environmental insults in childhood and that exposures early in life could increase the risk of breast cancer in adulthood.


Next Page Next Page |Chernobyl’s burden 1 2 3

Past Briefs

Print this article Print

OFF THE ROAD     IMPAIRED FERTILITY

email.gif